A feedback mechanism regulates monoallelic odorant receptor expression
نویسندگان
چکیده
منابع مشابه
A feedback mechanism regulates monoallelic odorant receptor expression.
In olfactory neurons, expression of a single odorant receptor (OR) from a repertoire of >1000 genes is required for odor coding and axonal targeting. Here, we demonstrate a role for OR protein as an essential regulator in the establishment of monoallelic OR expression. An OR-promoter-driven reporter expresses in a receptor-like pattern but, unlike a native OR, is coexpressed with an additional ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2004
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0307986100